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Article: Serum S100B Is Related to Illness Duration and Clinical Symptoms in Schizophrenia-A Meta-Regression Analysis.

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Schümberg K; Polyakova M; Steiner J; Schroeter ML
Front Cell Neurosci, 2016


Results of simple meta-regression of covariates with serum S100B effect size.

Covariate Number of studies Coefficient (β) r2 p
Mean age 19 0.0573 0.52 0.0026
Illness duration 16 0.0537 0.46 0.0086
Mean age at onset 16 0.1022 0 0.2329
Male-to-female ratio 19 0.0161 0 0.8444
PANSS total score 11 -0.0435 0.82 0.0014
PANSS positive 8 -0.1273 0.55 0.0228
PANSS negative 9 -0.0856 0 0.2766
PANSS general 7 -0.0965 1 0.0008
BPRS score 6 0.0339 0.25 0.1859
Bias index 19 0.3023 0.61 0.0010

Note: BPRS, Brief Psychiatric Rating Scale; PANSS, Positive And Negative Syndrome Scale.


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